Elmex fluid
Clinical indication(s) / Claim(s)
Verbatim per manufacturer's Instructions-for-use (IFU) sheet

IFU Link
Claim 1: Caries prophylaxis
Claim 2: Treatment of initial caries
Claim 3: Treatment of teeth sensitive to cold/hot









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Clinical evidence supporting the claim(s)
From full report(s) of prospective, clinical controlled trial(s)
Clinical evidence not supporting the claim(s)
From full report(s) of prospective, clinical controlled trial(s)
Clinical evidence not related to the claim(s)
From full report(s) of prospective, clinical controlled trial(s)
(c) RCHSR
CQ-Score of the publication
Criterion I = 1 Criterion II  = 0 Criterion III  = 0 / Total score = 0
Claim 1:
Kirschneck C, Christl JJ, Reicheneder C, Proff P. Efficacy of fluoride varnish for preventing white spot lesions and gingivitis during orthodontic treatment with fixed appliances-a prospective randomized controlled trial. Clin Oral Investig. 2016 Dec;20(9):2371-2378.

Splieth CH, Berndt C, Alkilzy M, Treuner A. Efficacy of semiannual topical fluoride application in schoolchildren. Quintessence Int. 2011 Oct;42(9):753-60.

Claim 1:
Brambilla E, Gagliani M, Felloni A, García-Godoy F, Strohmenger L. Caries-preventive effect of topical amine fluoride in children with high and low salivary levels of mutans streptococci. Caries Res. 1999 Nov-Dec;33(6):423-7.

Brambilla E, Toselli A, Felloni A, Gagliani M, Malerba A, Strohmenger L. The effect of biannual applications of amine fluoride solution on caries incidence in permanent first molars: a 5-year study. Int J Paediatr Dent. 1997 Mar;7(1):9-14.

Claim 2 and 3:
CQ-Score of the publication
Criterion I = 1 Criterion II  = 1 Criterion III  = 0 / Total score = 0
CQ-Score of the publication
Criterion I = 1 Criterion II  = 0 Criterion III  = 0 / Total score = 0
CQ-Score of the publication
Criterion I = 1 Criterion II  = 0 Criterion III  = 1 / Total score = 0